Protein Data Bank and AI

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Profile [VENETO] boboviz

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Message 113577 - Posted: 21 May 2026, 7:48:05 UTC

European Protein Data Bank now connected with the Alphafold Protein Structure Database directly to Claude and other MCP-compatible AI systems.

LLMs can describe protein structures.
But until now, they couldn’t actually access PDBe’s live data.

No fresh depositions.
No schema-aware search.
No graph exploration.
No structured retrieval.

So we built the bridge.

What can you build with it?

→ Ask Claude about any PDB entry in plain English.
→ Generate Cypher queries with schema awareness.
→ Build structural biology copilots.
→ Create lab assistants powered by live PDBe data.
→ Explore protein structure graphs interactively.

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Profile [VENETO] boboviz

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Joined: 1 Dec 05
Posts: 2193
Credit: 13,720,774
RAC: 791
Message 113582 - Posted: 28 May 2026, 15:52:28 UTC - in response to Message 113577.  

Connect Claude to PDBe in 3 steps:

1️⃣ Install uv
2️⃣ Run:
uvx pdbe-mcp-server --server-type pdbe_api_server
3️⃣ Add config to Claude Desktop

Now ask, for example:
“Find X-ray structures for UniProt P12345”

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Message boards : Rosetta@home Science : Protein Data Bank and AI



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